Copy the downloaded Fable3.exe (or the patched launcher) into your game directory, overwriting the existing file.
In many jurisdictions, creating a backup copy of software you legally own is permitted. A No CD patch falls under this "fair use" umbrella, provided you own the original DVD. If you do not own the game, downloading the patch is software piracy. fable 3 no cd patch free
A No CD patch alone won't fix GFWL. You will also need the "GFWL Disabler" (often called xlive.dll wrapper). Place this in the same game directory. This tricks the game into thinking GFWL is running when it is not. Copy the downloaded Fable3